Lyme Disease Skin Rash (Erythema Migrans)

An early sign of Lyme disease, caused by a tick bite (blacklegged/deer tick). The first symptom is often a spreading red rash called erythema migrans.

Where it happens

  • Common in certain regions (parts of North America and Europe) during warmer months.
  • Ticks are tiny; many people don’t notice the bite.

What the rash looks like

  • Starts at the site of the bite after 3–30 days (often 7–14 days).
  • Expands over days to more than 2 inches (5 cm), sometimes much larger.
  • Usually not very itchy or painful.
  • Can be uniformly red or have central clearing (“bull’s-eye”), but not always.
  • You may also feel like you have the flu: fatigue, headache, low fever, body aches.

Important: A small red bump right after a bite that stays under 2 cm and fades in a day or two is usually just a normal bite reaction, not Lyme.

When to see a clinician

  • Any expanding rash after a possible tick bite or outdoor exposure in a Lyme area.
  • If you have multiple rashes, severe headache, neck stiffness, facial droop, or joint swelling.

Diagnosis and treatment

  • In early rash stage, doctors often diagnose clinically without waiting for blood tests.
  • Antibiotics are very effective (for example, doxycycline for most adults; amoxicillin or cefuroxime in others). Courses are typically 10–21 days depending on the case.
  • Early treatment usually leads to full recovery.

Tick bite prevention

  • Use EPA-registered repellents (like DEET or picaridin).
  • Wear long sleeves and tuck pants into socks in brushy areas.
  • Treat clothing/gear with permethrin.
  • Do tick checks after being outdoors; shower soon after.
  • To remove a tick: use fine tweezers to grasp close to the skin and pull straight out; clean the area.

If you bring me your region, I can tailor prevention tips and typical tick activity timing for your area.

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