Tinea Manuum (Fungal Hand Rash) vs Eczema – How to Tell and Treat

A scaly hand rash can be fungus (tinea manuum) or eczema. Getting it right matters because treatments differ.

Tinea Manuum (Fungal Hand Infection)

  • Clues it’s fungus:
    • Usually one hand worse than the other (“two feet–one hand” pattern if athlete’s foot is present).
    • Ring-like, expanding scaly border on the palm or back of hand; can be dry and “moccasin-like” on the palm with fine scale.
    • Itches; may have small blisters.
    • Often coexists with tinea pedis (athlete’s foot) or nail fungus.
  • Tests:
    • A clinician can scrape scale for a KOH exam or culture to confirm.
  • Treatment:
    • Topical antifungals 2–4 weeks (terbinafine, butenafine, clotrimazole, ketoconazole).
    • For thick, chronic, or widespread cases, oral antifungals (terbinafine/itraconazole) may be needed.
    • Treat feet at the same time to prevent reinfection. Clean/disinfect shared items; keep hands/feet dry.

Hand Eczema (Dermatitis)

  • Clues it’s eczema:
    • Both hands (often), history of atopic dermatitis or sensitive skin.
    • Itchy, dry, cracked areas; may have tiny blisters on sides of fingers (dyshidrotic eczema).
    • Flares with soaps, wet work, cold weather, or specific products (possible contact allergy).
  • Treatment:
    • Gentle care: fragrance-free cleanser, moisturize after every wash with thick creams/ointments.
    • Short courses of topical steroids for flares; non-steroid anti-inflammatories for maintenance.
    • Patch testing if allergic contact dermatitis is suspected.

Quick tip to differentiate

  • Unilateral scaly annular patch with active border + athlete’s foot = think tinea.
  • Symmetric dry, fissured hands worse with washing/chemicals = think eczema.

When to see a clinician

  • If home antifungal or eczema care fails after 2–4 weeks.
  • Painful cracks, signs of infection (pus, yellow crust, fever).
  • To test and choose targeted therapy.

Prevention

  • Keep hands dry between fingers; use cotton glove liners under nitrile for wet work.
  • Don’t share towels; clean gym gear; wear sandals in locker rooms.
  • Moisturize routinely; avoid harsh soaps.

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